Cancer New skull breaking open/neck crackling/fluid sensations with weed use

Hello, I joined the forums just for this post, so forgive me if I am doing something incorrectly.

I have been using medical marihuana for a couple of years now to treat chronic nerve/joint/muscle pain and more recently chemotherapy related side effects. The positives for me have always outweighed the negatives, until recently.

My team of doctors are aware that I use MMJ however are not incredibly familiar with it nor do they have a firm grasp on my symptoms or what is happening to me outside of my brain tumor as it is. I do plan to bring this up with them, I just feel that you all would potentially have more answers for me.

Every time I use, even a little bit, even really good stuff, no matter the form, I have been getting the intense and long lasting sensation that my skull is splitting open, that warm fluid is accumulating at the top of my skull and dripping down my neck, that my neck and head are crackling and will break off if I move. Laying down, sitting up, distracted, focused, indicas or sativas. I will get the unique effects of the strain for a few minutes and then this comes crashing in. I try to be mindful. I tell myself that I know weed cannot harm me, that its in my head, to refocus on the tingling aspects and think of them that way. And it works minimally for a short time, but continues regardless. I feel that it remains long after the effects have worn off.

I took a week break. I've been drinking more water especially before and during. Ive tried relaxing environments and friends and shows and activities. Still, it persists. Its agonising and terrifying. I don't want to stop using, I cannot afford to stop using, my pain is not responsive to anything else. And yet, I am completely turned off from it now.

I have been googling everything and every circumstantial thing and every wording I can think of and have found no similar stories.

My thoughts as to possible precedents include:

My third round of chemotherapy. Specifically lomustine, vincristine, and procarbazine. These cause progressive nerve damage, could my nerves have changed to where pleasure signals are disrupted and altered?

Overdosing on an edible: around the time that this all started, I had overestimated my tolerance and had a very bad trip with these symptoms and psychosis and more. I have since taken a T break. Could I just need a longer time free of THC?

Finally, in desperation, I was adding a thca tincture to low grade weed in my vape for a while before I could renew my stash. Could this have done permanent/semi permanent damage in some way?

I feel incredibly stupid, and afraid, and miserable with untreated pain. Please, be gentle with me. Thanks in advance to anyone who has any insight!

 

This is a good idea, thank you. And thank you for the reassurance. I am trying to remind myself that anxiety can do a lot of things even when not conscious of it, especially combined with the fact that my skull has been cut into and plated just a year ago. I guess a lot of strange things can happen.

 

Thank you! All very helpful and appreciated!

 

Coming back to update and to answer some questions.

Firstly, I have continued to abstain from cannabis use for the time being. I am hoping one of the doctors on my team will be willing to look into and discuss this with me, particularly as this is something that could effect other patients.

I have not gotten into the concentrated RSO oil thus far, mostly as I only have a small budget and I need for it to go to relief. I use a pax vaporizer as well as edibles, lozenges, concentrates/dabs, and tinctures. I tend towards indicas.

This has been occuring with every strain and every method of consumption. I recently tried some CBD again and had the exact same effects...curiouser and curiouser.

My mental health counselor agrees that this seems to be more than the effects of anxiety, she told me it sounded like an interaction. And I am inclined to agree.

Two findings of interest: the one chemo drug with the highest neurotoxicity profile has a known but difficult to find interaction with cannabis. Specifically, it acts on the pump mechanisms and increases the serum levels. Hmm.

I am also waiting to get access to a study I found on cannabis possibly having effects like tyramine- something that I am restricted from having with Procarbazine due to the MAOI like interaction.

Two possibilities. Unsure if they could be causing these symptoms. The Vincristine is the one I am most suspicious of, and also have a chance of being taken off of as data is insufficient as to theraputic value and it is a rough drug to be on.

Finally, I have tested my blood pressure several times before, during, and after usage. My BP is low as is, and I found that there were very minimal effects on mine. When there were effects, my systolic was dropping slightly lower.

Thanks all for continued suggestions and replies. I really hope to figure this out even just to sate my own research curiosity. Will keep you all updated!

 

ETA: I also use topicals/transdermal patches. I am unsure if these would contribute the same effects as they do not get me high.

 

I figure I may as well add just in case it holds any possible relevance, my tumor is a diffuse/anaplastic astrocytoma (characteristics on the cusp of grade II and III), I have had two surgeries (over a year ago now), radiation, and three rounds of PCV chemotherapy. I am also Autistic and have Ehlers Danlos Syndrome which is a genetic condition effecting the whole body.

 

I have had another revelation relating to one specific aspect of this experience: scar tissue. At my incision cite. Cutting across the top of my skull. The cannabis could be increasing blood flow to the area and causing me to feel both that blood is pooling in the tissue (and possibly forming knots of muscle) but also that this engorgement combined with the intensified awareness of my nerves there (likely entrapped in scar tissue) could very well full like it's pulling because it *is*, and thus the ripping sensation.

Put together with the fact that pot relaxes my muscles and my joints are held together mainly by faulty collagen and muscle, very tight muscle, and I've got a recipe for disaster. My joints become more injured more when my muscles are loose and my nerves are mixed up and create post-high tension greater than before.

The only thing I am wondering now is why it's only just started to feel this way.

I've gotten the bad effects with my joints before but usually counteracted or neutralized by the level of relief. The scar tissue isn't exactly new...