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Please share a Interesting facts about marijuana!

Discussion in 'Medical Marijuana News' started by Chrisfrancy, Mar 5, 2018.

  1. I just want to know more about marijuana. So is there any interesting facts and if yes then please share with me waiting for your response.

  2. It gets you high.
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  3. #4 Storm Crow, Mar 5, 2018
    Last edited: Mar 5, 2018
    Cannabis use greatly increases your odds of surviving a major head trauma! :smoke: (The link is to a short abstract, so you won't need to read 15 pages of "sci-speak".)

    Effect of Marijuana Use on Outcomes in Traumatic Brain Injury. Effect of marijuana use on outcomes in traumatic brain injury. - PubMed - NCBI

    In this study it was found that “Overall mortality was 9.9 per cent, however, mortality in the THC(+) group (2.4%) was significantly decreased compared with the THC(-) group (11.5%)”.

    I think those stats rather eye-opening! Cannabis is a powerful neuroprotectant! The study was done in San Francisco in 2014. I hope to see it repeated in the future, and the results confirmed.

    I'll be back! And I'll drop more "goodies" on you all!

    Granny :wave:
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  4. So according to you, marijuana harms the the brain right
  5. Thanks dear for the reply
    • Funny Funny x 1

  6. Someone was gonna reply with it so i though I'd beat em to it lol, other facts are certain strains help with pain
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  7. Granny says the study helps those survive a head trauma.

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    • Agree Agree x 1
  8. @chris, do you normally have trouble with reading comprehension? Please re-read what I posted! Cannabis PROTECTS YOUR BRAIN!

    And @ the rest of you, here's an article and some more studies, as promised- This time on Alzheimer's.

    Marijuana May Slow Alzheimer's (news - 2006) Marijuana May Slow Alzheimer's

    “THC blocks an enzyme called acetylcholinesterase, which speeds the formation of amyloid plaque in the brains of people with Alzheimer's disease. The Alzheimer's drugs Aricept and Cognex work by blocking acetylcholinesterase. When tested at double the concentration of THC, Aricept blocked plaque formation only 22% as well as THC, and Cognex blocked plaque formation only 7% as well as THC.” From “Marijuana May Slow Alzheimer's” at WebMD.

    So if Aricept works, then THC works even better. :eek2:

    That WebMD article is based on the study, “A Molecular Link between the Active Component of Marijuana and Alzheimer’s Disease Pathology” http://www.ukcia.org/research/AlzheimersDiseasePathology.pdf where “It is noteworthy that THC is a considerably more effective inhibitor of AChE-induced A‚ deposition than the approved drugs for Alzheimer’s disease treatment, donepezil and tacrine, which reduced A‚ aggregation by only 22% and 7%, respectively, at twice the concentration used in our studies. Therefore, AChE inhibitors such as THC and its analogues may provide an improved therapeutic for Alzheimer’s disease, augmenting acetylcholine levels by preventing neurotransmitter degradation and reducing A‚ aggregation, thereby simultaneously treating both the symptoms and progression of Alzheimer’s disease.”

    (FYI - AChE= acetylcholinesterase; A, = amyloid plaque; donepezil and tacrine = Aricept and Cognex)

    Now, THC will get you “high” by activating the CB1 receptors :smoking:, but THC also activates the healing CB2 receptors, and then this can happen- “The activation of cannabinoid CB2 receptors stimulates in situ and in vitro beta-amyloid removal by human macrophages” The activation of cannabinoid CB2 receptors stimulates in situ and in vitro beta-amyloid removal by human macrophages. - PubMed - NCBI .
    Or you might prefer the shorter news article on the study, “Cannabinoids remove plaque-forming Alzheimer's proteins from brain cells” Cannabinoids remove plaque-forming Alzheimer's proteins from brain cells .

    (FYI- in situ means on the site, in this case in a brain; in vitro means in a test tube; macrophages are your “clean up crew” cells.)

    But activating the CB2s can do some even more remarkable things! “Activation of the CB(2) receptor system reverses amyloid-induced memory deficiency” Activation of the CB2 receptor system reverses amyloid-induced memory deficiency. - PubMed - NCBI . So not all memory is lost forever in Alzheimer's! CB2 activation can restore some (but not all) memory!

    And for the “Tau”ists who believe that "tau tangles" are more to blame for causing Alzheimer's - “Natural Cannabinoids Improve Dopamine Neurotransmission and Tau and Amyloid Pathology in a Mouse Model of Tauopathy” Natural Cannabinoids Improve Dopamine Neurotransmission and Tau and Amyloid Pathology in a Mouse Model of Tauopathy - IOS Press

    In this study, they used Sativex, an alcohol extract of cannabis (a legal medicine in Canada and much of Europe) where “With regard to tau and amyloid pathology, Sativex® reduced the deposition of both in the hippocampus and cerebral cortex of PK-/-/TauVLW mice and increased autophagy. Sativex®, even after a short administration in animals with present behavioral and pathological abnormalities, improves the phenotype, the oxidative stress, and the deposition of proteins in PK-/-/TauVLW mice, a model of complex neurodegenerative disorders.”

    (FYI - hippocampus and cerebral cortex are parts of the brain; autophagy is one way a damaged cell can die; and basically, this study says that even a short time of using Sativex made the mice act more normally. )

    Then you might add some Omega 3 to boost the health of your endocannabinoid system and also do this - “Omega-3 polyunsaturated fatty acids promote amyloid-β clearance from the brain through mediating the function of the glymphatic system” Omega-3 polyunsaturated fatty acids promote amyloid-β clearance from the brain through mediating the function of the glymphatic system. - PubMed - NCBI
    And maybe when you hit 70, you'll still be feeling half your age and reading medical studies, like me. :ladiegaga:

    Granny :wave:
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  9. If you have, or know someone who suffers from, Crohn's disease, you know that patients with this decision have a defect in the intestines that allows bacteria to leak into the intestinal tissue causing inflammation and pain. It can also lead to a secondary condition known as Ulcerative Colitis, where the tissue can rupture and bleed.

    Current medical knowledge suggests that both of these diseases are caused by a combination of genetic and environmental factors, meaning that people with the genetic pre-disposition for these conditions who are then subjected to the environmental triggers - stress, poor diet, bacterial infections - are likely to develop the actual diseases.

    So where does cannabis come in?

    Recent research done in the UK has shown that two of the compounds found in marijuana, CBD (cannabidiol) and THC, do interact with intestinal function, lending credence to a lot of anecdotal evidence that medical marijuana is an effective treatment for many inflammatory bowel diseases, including Crohn's.

    The British researchers found that cannabinoids derived from actual plants (as opposed to synthetics), encourage tighter bonds between the cells that form the barrier in the gut that prevents bacterial leakage. This information is new, though it's long been known that cannabis is an anti-inflammatory, which also helps treat the symptoms of Crohn's disease.

    In addition to reducing inflammation and helping to regenerate bowel tissue, medical marijuana also helps ease the cramps associated with intestinal irritation and boosts the appetite. While the appetite stimulation qualities of cannabis are known to be vital for cancer and AIDS patients, they're equally important for patients with ulcerative colitis and Crohn's whose leaky guts prevent the absorption of essential nutrients.

    What kinds of marijuana are best for treating bowel conditions? Most patients recommend Indica strains as they have the strongest muscle relaxing effects. Specific strains used to treat these conditions include Auntie Em, Blue Fruit, and Dynamite.
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  10. THC is one of the finest methods of treating PSTD and ADD/ADHD as it corrects several chemical imbalances in the brain that are associated with these conditions. I have no links but there is plenty of easy to find research on this.

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