No, as MH and HPS lights run differently. They do, however, make conversion light bulbs to allow the use of a MH in an HPS socket and vice versa. The light does lose a bit of wattage; a 400w light would become about 350-360w with a conversion bulb. Then again, if using an MH socket and a HPS bulb, the lumen output of the HPS is greater than an MH, so even with the wattage loss, you still should gain some lumens, if not break even. ~Lycanthropy