A group of scientist came together and did a study, and concluded that the main chemical in cannabis (THC) can prevent and treat alzheimer's disease...Full article here: http://marijuanawiki.ml/2016/08/26/thc-in-marijuana-can-prevent-alzheimers/
That's been known for a decade! If you had you own copy of "Granny Storm Crow's List", you'd know that, hon! WebMD had this info way back in 2006! Marijuana May Slow Alzheimer's (news - 2006) Marijuana May Slow Alzheimer's “THC blocks an enzyme called acetylcholinesterase, which speeds the formation of amyloid plaque in the brains of people with Alzheimer's disease. The Alzheimer's drugs Aricept and Cognex work by blocking acetylcholinesterase. When tested at double the concentration of THC, Aricept blocked plaque formation only 22% as well as THC, and Cognex blocked plaque formation only 7% as well as THC.” That article is based on the study- A Molecular Link between the Active Component of Marijuana and Alzheimer’s Disease Pathology (full - 2006) http://www.ukcia.org/research/AlzheimersDiseasePathology.pdf “It is noteworthy that THC is a considerably more effective inhibitor of AChE-induced A‚ deposition than the approved drugs for Alzheimer’s disease treatment, donepezil and tacrine, which reduced A‚ aggregation by only 22% and 7%, respectively, at twice the concentration used in our studies. Therefore, AChE inhibitors such as THC and its analogues may provide an improved therapeutic for Alzheimer’s disease, augmenting acetylcholine levels by preventing neurotransmitter degradation and reducing A‚ aggregation, thereby simultaneously treating both the symptoms and progression of Alzheimer’s disease.” (FYI- AChE= acetylcholinesterase, it speeds the formation of amyloid plaque in your brain; A, = amyloid plaque; donepezil and tacrine = Aricept and Cognex) But THC doesn't stop at "just" preventing the deposit of amyloid plaque! THC activates both the "high" producing CB1 receptors, and also the no "high", but great at healing, CB2 receptors! And look what happens when the CB2s get activated! The activation of cannabinoid CB2 receptors stimulates in situ and in vitro beta-amyloid removal by human macrophages. (abst - 2009) The activation of cannabinoid CB2 receptors stimulates in situ and in vitro beta-amyloid removal by human macrophages. - PubMed - NCBI Activation of the CB(2) receptor system reverses amyloid-induced memory deficiency. (abst – 2013) Activation of the CB2 receptor system reverses amyloid-induced memory deficiency. - PubMed - NCBI So cannabis "tells" your macrophages to "take out the (amyloid) trash"! Removing the amyloid plaque apparently can restore some "lost" memory! And for the "Tauists", cannabis works on Tau tangles, too! Natural Cannabinoids Improve Dopamine Neurotransmission and Tau and Amyloid Pathology in a Mouse Model of Tauopathy. (link to PDF – 2013) Natural Cannabinoids Improve Dopamine Neurotransmission and Tau and Amyloid Pathology in a Mouse Model of Tauopathy - IOS Press And finally, to quote Dr.Gary Wenk, professor of neuroscience, immunology and medical genetics at Ohio State University- “ .. if you do anything, such as smoke a bunch of marijuana in your 20s and 30s, you may wipe out all of the inflammation in your brain and then things start over again. And you simply die of old age before inflammation becomes an issue for you,” and "individuals who smoked marijuana in the ‘60s and ‘70s, who are now entering their 60s and 70s, are not getting Alzheimer’s at the rate they should be." Oh, and here's the study that the OP's article is based on- Amyloid proteotoxicity initiates an inflammatory response blocked by cannabinoids (full – 2016) Amyloid proteotoxicity initiates an inflammatory response blocked by cannabinoids : npj Aging and Mechanisms of Disease Want to learn more about what cannabis can do? Get your free copy of "Granny Storm Crow's List"! Granny's List is on the Cloud! FREE! Get it here! Granny's List is on the Cloud! FREE! Get it here! There's a LOT more to cannabis than just getting "high"! Granny