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What does CBG do?

Discussion in 'Medical Marijuana Usage and Applications' started by tstick, Sep 24, 2013.

  1. Some strains of weed are now showing up with CBG % on the label. Someone said it's a THC multiplier. What does that mean and what does this cannabinoid do?
     
    Thanks

     
  2. I dont know a ton about it , I know its non psychoactive, especially useful for eye pressure related to glaucoma from what I hear. Hopefully more and more studies are done soon on all the cannibinoids.
     
  3. Granny to the rescue! :laughing:  Here's the CBG section from my List. (If you had a copy of the List, you could have just looked it up yourself!- To get yours, check out the bottom of my sig, or PM me your email!)
     
    \tCBG/ CANNABIGEROL* - [SIZE=10pt]phytocannabinoid,[/SIZE] [SIZE=10pt]CB2 agonist[/SIZE]\nPhytocannabinoids          (news – undated)
    http://www.news-medical.net/health/Phytocannabinoids.aspx
     
    Cannabinoids in clinical practice.        (abst - 2000)  http://www.ncbi.nlm.nih.gov/pubmed/11152013
     
    Antibacterial cannabinoids from Cannabis sativa: a structure-activity study.   (full - 2008)
    http://www.scribd.com/doc/7718968/Antibacterial-Cannabinoids-From-Cannabis-Sativa-A-StructureActivity-Study
     
    Patent application title: THERAPEUTIC USES OF CANNABIGEROL      (full - 2010)
    http://www.faqs.org/patents/app/20100292345
     
    Evidence that the plant cannabinoid cannabigerol is a highly potent alpha2-adrenoceptor agonist and moderately potent 5HT1A receptor antagonist.        (full - 2010)
    http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2823359/?tool=pubmed
     
    Antidepressant-like effect of Delta(9)-tetrahydrocannabinol and other cannabinoids isolated from Cannabis sativa L.          (full - 2010)   http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2866040/?tool=pubmed
     
    Detection of cannabigerol and its presumptive metabolite in human urine after Cannabis consumption.       (abst - 2010)          http://www.ncbi.nlm.nih.gov/pubmed/20614687
     
    Evaluation of the Cyclooxygenase Inhibiting Effects of Six Major Cannabinoids Isolated from Cannabis sativa         (full – 2011)       https://www.jstage.jst.go.jp/article/bpb/34/5/34_5_774/_pdf
     
    Phytocannabinoids for use in the treatment of cancer   -  Patent  GB2478595  (A) ― 2011-09-14          (full – 2011) http://worldwide.espacenet.com/publicationDetails/biblio?CC=GB&NR=2478595A&KC=A&FT=D&ND=&date=20110914&DB=&locale=en_EP
     
    Interaction between non-psychotropic cannabinoids in marihuana: effect of cannabigerol (CBG) on the anti-nausea or anti-emetic effects of cannabidiol (CBD) in rats and shrews.
                (abst – 2011)       http://www.ncbi.nlm.nih.gov/pubmed/21243485
     
    Plasma and brain pharmacokinetic profile of cannabidiol (CBD), cannabidivarine (CBDV), Δ(9)-tetrahydrocannabivarin (THCV) and cannabigerol (CBG) in rats and mice following oral and intraperitoneal administration and CBD action on obsessive-compulsive behaviour.       (abst – 2011)       http://www.ncbi.nlm.nih.gov/pubmed/21796370
     
    Effects of cannabinoids and cannabinoid-enriched Cannabis extracts on TRP channels and endocannabinoid metabolic enzymes.         (abst – 2011) http://www.unboundmedicine.com/medline/ebm/record/21175579/abstract/Effects_of_cannabinoids_and_cannabinoid_enriched_Cannabis_extracts_on_TRP_channels_and_endocannabinoid_metabolic_enzymes_
     
    Phytocannabinoids as novel therapeutic agents in CNS disorders      (abst – 2012)
    http://www.ncbi.nlm.nih.gov/pubmed/21924288
     
    A Cannabigerol Quinone Alleviates Neuroinflammation in a Chronic Model of Multiple Sclerosis.    (abst – 2012)      http://www.ncbi.nlm.nih.gov/pubmed/22971837
     
    Analysis of cannabinoids in laser-microdissected trichomes of medicinal Cannabis sativa using LCMS and cryogenic NMR.        (abst – 2012)  http://www.ncbi.nlm.nih.gov/pubmed/23280038
     
    5 Marijuana Compounds That Could Help Combat Cancer, Alzheimers, Parkinsons (If Only They Were Legal)      (news – 2012)   
    http://www.alternet.org/drugs/5-marijuana-compounds-could-help-combat-cancer-alzheimers-parkinsons-if-only-they-were-legal
     
    Beneficial effect of the non-psychotropic plant cannabinoid cannabigerol on experimental inflammatory bowel disease.      (abst – 2013)     http://www.ncbi.nlm.nih.gov/pubmed/23415610
     
    The effect of CBG (BDS) botanical cannabinoid extract on MCF-7 human breast carcinoma cells         (abst – 2013)  http://www.fasebj.org/cgi/content/meeting_abstract/27/1_MeetingAbstracts/1105.21?sid=eea722c0-971c-4daa-8b8c-38c0c63c19ad
     
    Epigenetic Control of Skin Differentiation Genes by Phytocannabinoids       
    (abst – 2013)       http://www.ncbi.nlm.nih.gov/pubmed/23869687
     
     
     
     
     
     
     
    Granny
     
  4. CBG helps treat inflammation. Weather it's IBS/IBD, arthritis, or pain related to inflammation, higher CBG is a good thing. This is also why it is effective at treating glaucoma related eye pressure.
     
    As far as a multiplying effect, I guess if you're using Cannabis for inflammation CBG would seem to have a multiplying effect because the medication would be more effective. I don't think you would notice any cerebral difference because of the CBG. 
     
    I'm sure there's more info out there but I hope that helps.
     

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