Sure, its possible. You probably won't get a whole lot yield-wise, but you gotta do what you gotta do. Think about LST, it will help get a little more plant in a smaller space.
You can grow in the smallest of spaces. I'm presently growing in a cab that is just over 2.5 sq ft and using T-5 HO flourescents. I have produced just under 2 oz's in this space. In smaller places you want good air flow, and use small containers. I use 3 gl for 2 plants, right now I'm doing a few in 1 gl containers which will hopefully end in 3 plants, and will grow them just over 2 ft when finished. Just keep a close eye on your temps, small spaces heat up quick, so a good airflow is a must.