Identification of candidate genes affecting THC biosynthesis in Cannabis sativa

Discussion in 'Science and Nature' started by Loki7, Sep 25, 2010.

  1. Ever wonder what genes are active in those frosty trichomes making that stony goodness?

    Identification of candidate genes affecting Δ9-tetrahydrocannabinol biosynthesis in Cannabis sativa

  2. Very interesting stuff. Does this give us any clues as to the role of THC for the plant? The article mentions similarities to a substance produced by glands in female hop plant that is thought to have some antibiotic properties.

    This could be the basis of some real insights into THC, which has been seriously lacking for a substance of such wide use and possible medicinal use.
  3. #3 Loki7, Sep 26, 2010
    Last edited by a moderator: Sep 26, 2010

    To me, I see two very useful things... really they are the same thing. With the mRNA sequenced (or rather the cDNA that comes from the mRNA) we know the genes that are active, so we can eliminate all the genes that aren't active. This creates a much smaller pool of DNA to fish in. That in itself is huge. But more importantly, they've identified the missing link, even though they themselves didn't realize it.

    CBG... mysterious CBG... a prenyltransferase, but more than that...


    It's a membrane bound prenyltransferase, a CBG pump, if you will... It completes the THC biosynthesis pathway and opens the doors to cannibinoids in other plants.

  4. thc tomatos xD

Share This Page