Using a rotary evaporator is a necessary step in many experiments, which enables solvents gently and efficiently separate from samples. In some cases, the rate of rotary evaporation isn’t an issue, such as when you have very little solvent to evaporate or if time simply doesn’t matter. However, in most cases, you want the evaporation process to be as fast as possible, especially if you’re running the application multiple times in succession or dealing with large volumes. Here are 5 ways to make your laboratory evaporation speed faster: Increasing the evaporation flask size. Increasing the evaporation flask rotating speed. Increasing the rotary evaporator’s bath temperature. Increasing the vacuum level. Monitoring the height of the condensed solvent on the coils of the condenser. 1.Increasing the evaporation flask size Larger flasks have a larger surface area, which helps speed up the evaporation process. If you choose a beaker, please consider that once you have completed the beaker, the larger opening will make it easier for you to collect the product and it will be cleaned faster. For laboratory research, choosing a small rotary evaporator is more economical and practical. But if you want to create a more effective rotary evaporation method, the larger the better. Since the larger flask has a larger surface, this will cause more flasks to come into contact with the water/oil bath, thereby heating the sample more uniformly and faster, which increases the evaporation speed. In short, a larger flask will expose the surface of the sample to the air inside the flask, ultimately making the evaporation process more efficient. In addition to efficiency, there are practical implications for using undersized containers. Since the flask was tilted during the installation of the rotary evaporator, if the flask is too full, there is more chance of overflow. Ideally, more than half of the evaporation flask should not be filled to prevent spillage, and sufficient liquid surface area should be left for effective rotary evaporation. 2.Increasing the evaporation flask rotating speed The second important factor in the setup of a rotary evaporator is the speed at which the evaporation flask rotates. The rotation of the flask has two main functions. First, it agitates the water bath to improve heat transfer to the flask and solvent. In addition, the rotation increases the surface area of the liquid in the flask, thereby increasing the evaporation rate. It is recommended to change the rotation speed of the distillation flask from 120-310rpm (it will be different for different capacity rotary evaporators and different samples), which will increase the surface area of the solution and increase the rotary evaporation rate of the solvent. 3.Increasing the rotary evaporator’s bath temperature The water bath is one of the ways to accelerate evaporation by rotary evaporation. It heats the solvent, increasing the evaporation rate. If the temperature is set too high, the evaporating temperature also depends on the refrigerator you are using. This will increase the evaporation rate and keep the refrigerator from keeping up with the temperature. Therefore, we can slowly heat the water bath of the rotary evaporator, it is recommended that 30-40 ℃, the temperature of the condenser controlled by the low-temperature circulating water bath cooler can be set from -10 ℃ to 0 ℃. 4.Increasing the vacuum level One of the main reasons for using a rotary evaporator is to reduce the boiling temperature of the solvent by using a vacuum to reduce the pressure in the system. Therefore, it is helpful to increase the vacuum and further reduce the pressure. Indeed it is. If the vacuum increases too fast or too fast, it may bump (as described above) or foam. Foam occurs when a surfactant is included in the sample and small bubbles (foam) appear on the surface. This can usually be alleviated by carefully monitoring the sample and slowly increasing the vacuum. Reducing the pressure in the system will also cause the evaporation speed to be too fast. If the solvent does not have time to evaporate in the condenser, uncondensed vapor may enter the vacuum pump. Finally, excessive vacuum increases the risk of glassware implosion.