Please post only if you are taking an SSRI. I've been taking Zoloft, 100 mg for about 3 years for anxiety, and I've recently discovered the day after I smoke weed, or when later in the day after I'm no longer high, I feel really shitty. Depressed, hate life.... that kind of thing. I haven't smoked weed in about 3 weeks and I feel terrific. Do any of you SSRI users have similar experiences?