Logic Pro 9... Music production program... pretty sick.. I use Ableton for my live shit because it's easier to program on the fly.
Sorry, but I have a 7-way tie. Logic Pro Mackie Tracktion Ampeg SVX (and amplitube, since it's all the same) Ventrilo Team Fortress 2 Photoshop Firefox.
jungleflasher and abgx one is used to flash xbox 360 disc drives the other it cross check downloaded games
Logic Pro 8 (Music production) Aperture (Photography) Traktor (Music mixing) Itunes (and my nifty TuneUp addon that cleans all of my music )
Microsoft calculator Where would the world be without it Looking for their physical calculator most likely.