Association of Cannabis Use in Adolescence and Risk of Depression, Anxiety, and Suicidality in Young

Discussion in 'Marijuana News' started by trojangrower, Feb 14, 2019.

  1. Published in JAMA Psychiatry, Feb 13 2019 here (linked).

    Key Points

    Question Is adolescent cannabis consumption associated with risk of depression, anxiety, and suicidality in young adulthood?

    Findings In this systematic review and meta-analysis of 11 studies and 23 317 individuals, adolescent cannabis consumption was associated with increased risk of developing depression and suicidal behavior later in life, even in the absence of a premorbid condition. There was no association with anxiety.

    Meaning Preadolescents and adolescents should avoid using cannabis as use is associated with a significant increased risk of developing depression or suicidality in young adulthood; these findings should inform public health policy and governments to apply preventive strategies to reduce the use of cannabis among youth.

    Bit of a rough finding; could have cherry picked? idk.
    Rest of it linked above.
     
  2. I doubt they could find enough adolescents that were NOT already on a Psychiatry prescribed medication to run a valid test.
    Don't want any competition as it might cut into sales of

    Most Frequently Prescribed Psychotropic Drugs
    • Xanax (alprazolam), 48.5 million.
    • Zoloft (sertraline), 41.4 million.
    • Celexa (citalopram), 39.4 million.
    • Prozac (fluoxetine), 28.3 million.
    • Ativan (lorazepam), 27.9 million.
    • Desyrel (trazodone HCL), 26.2 million.
    • Lexapro (escitalopram), 24.9 million.
    Cannabis = Bad.

    1. Zoloft (sertaline) – Depression
    2. Xanax (alprazolam) – Anxiety
    3. Lexapro (escitalopram) – Depression
    4. Celexa (citalopram) – Depression
    5. Wellbutrin (bupropion) – Depression
    6. Desyrel (trazodone) – Anxiety, Depression
    7. Prozac (fluoxetine) – Depression
    8. Adderall (dextroamphetamine and amphetamine) – ADHD
    9. Ativan (lorazepam) – Anxiety
    10. Cymbalta (duloxetine) – Depression
    11. Effexor (venlafaxine) – Depression
    12. Seroquel (quetiapine) – Bipolar disorder, Depression
    13. Concerta (methylphenidate) – ADHD
    14. Kapvay (clonidine) – ADHD
    15. Lamictal (lamotrigine) – Bipolar disorder
    16. Paxil (paroxetine) – Depression
    17. Elavil (amitriptyline) – Depression
    18. Remeron (mirtazapine) – Depression
    19. Vyvanse (lisdexamfetamine) – ADHD
    20. Depakote (divalproex) – Bipolar disorder
    21. Risperdal (risperidone) – Bipolar disorder, Schizophrenia
    22. Abilify (aripiprazole) – Bipolar disorder, Depression, Schizophrenia
    23. Zyprexa (olanzapine) – Bipolar disorder, Schizophrenia
    24. Intuiv (guanfacine) – ADHD
    25. Lithium (lithium carbonate) – Bipolar disorder
    But this natural plant is Toxic. Sure it is.
    I think there is an Israeli study along the same lines with very different results.
    Then the next question is who funded the JAMA study :)
    BNW
     
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  3. Very good question...I just asked the lead author. We'll see if she responds.
     
  4. *This research was funded by the Canadian Institutes of Health Research (CIHR) and the Quebec Network on Suicide, Mood Disorders and Related Disorders.

    That being said, the lead author is an assistant professor trying to get published. Its also a meta-analysis review, and I would ask what the criteria for accepting older material was.
     
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