The fact you have even posted this, tell's me you are a senseable (watch the spelling) guy. The only thing it will do to you is probably make you a little more drowsey.
Smoked on Zoloft- towards the end when I wanted to get off that fucking drug. Like lerrox said- antidepressants are usually the problem. I was on Effexor first, which is a really fucked up drug- then on to zoloft, which did nothing, to dicovering pot which finally got me off antidepressants. This was just me though- obviously individuals may find different results.