yea u can use a aerogarden but u aint gonna get no dank ass bud as if u were to build a bubble bucket, or just use plain soil and the right MH lighting with the HPS for the flowering. the lighting on the aerogarden isnt that good for cannibis so i hear but its all on u, and yes it will work but u can only let your plant get so tall in one of those things i would think before it flowers, they only can go so high i believe, i guess u could always add additional lighting never thought about that, look up how to grow weed in a aero garden on u tube there is alot on there that will help ya out playa!!!