It would have to be diluted. You would not want to take one drop of pure lsd, you would lose your mind no doubt. Remember, an average dose is like the equivalent to a grain of sand.
theres documentation (ChinaCat) of people eating lsd CRYSTAL this is likely 1000's to 100,000 (depends on how much, but a solid active dose is around 150mics, so that would be literally microscopic, so if you are eating pure crystal theres no telling how much you could get) and these guys are still fine