Good/funny things about getting old...

it's no longer statutory

 

Lmfaoo

 

Eventually it will hurt to take a piss and people will get angry at you while you drive even when driving normally.

 

U earn the age you are so dont worry be happy stay high and do whatever the fuck you want.

 

As you get older you look less and less suspicious to cops

 

Shit in a box and give it to your kids, say it was a train set

Oh Nick Swardson

 

Yeah thats GOOD

"V"

 

Forgetfulness is totally excusable...

 

You can be crazy as FUCK and people will chalk it up to "oh... she's just old."

 

Senility xD

 

No curfew!

Clerks will load your groceries for you! (If someone offers to do the physical work, I'm fine with that! )

And fill Grandma in on this - a secret way to slow those wrinkles AND fight off Alzheimer's!

Early onset of aging-like changes is restricted to cognitive abilities and skin structure in Cnr1(-/-) mice.
(abst – 2011) Early onset of aging-like changes is restric... [Neurobiol Aging. 2010] - PubMed - NCBI

Don't worry, I'll talk you through this. You are about to become the "family genius" and her favorite grandchild! lol (This might work with your Mom, too!)

First, two terms you'll need to know!

Cnr1(-/-) mice = mice bred so they don't have CB1 receptors. Also called "CB1 knock-out mice".

CB1 receptors = These are chemical receptors on the surface of your cells. They tell a cell what to do. CB1s are activated by THC and Anandamide (your body's own version of THC). CB1s are responsible for getting you high and about 1000 other things.

(You can skip this and just read the translation! lol )
Genetic deletion of the cannabinoid 1 (CB1) receptor leads to an early onset of learning and memory impairment. In the present study we asked whether the lack of CB1 receptors accelerates aging in general or is selective for cognitive functions. We therefore compared the onset and dynamics of age-dependent changes in social memory, locomotor activity, hearing ability, and in the histopathology of peripheral organs between wild-type and Cnr1 knockout (Cnr1(-/-)) mice. We observed deficits in social memory already in 3-month-old Cnr1(-/-) mice. In contrast, wild-type animals showed such deficits at the age of 6 months. Sensory and motor functions were similar between the genotypes. Thus, hearing loss for higher frequencies and the development of hypomotility showed a similar age-dependent course. In the periphery we detected an early onset of aging-like histological changes in the skin, but not in other organs. We conclude that the lack of CB1 receptor does not induce accelerated aging in general, but induces changes in cognitive function and in skin structure that resemble those associated with aging.


Granny's translation - Cnr1(-/-) mice look older and go senile faster than normal mice. They start getting senile and start losing their hearing like mice twice their age. Other organs don't seem to age faster- "just" their skin, hearing and brain are affected by the lack of CB1 receptors.

Now, for part 2 of the anti-aging info! You only need to understand one sentence of this one!

Nutritional omega-3 deficiency abolishes endocannabinoid-mediated neuronal functions. (abst – 2011) Unbound MEDLINE | Nutritional omega-3 deficiency abolishes endocannabinoid-mediated neuronal functions. PubMed Journal article abstract

In n-3-deficient mice, presynaptic cannabinoid CB(1) receptors (CB(1)Rs) normally responding to endocannabinoids were uncoupled from their effector G(i/o) proteins.

Granny's translation- Mice without Omega 3 in their diet can't make working CB1 receptors. No Omega 3 and you are like those poor Cnr1(-/-) mice! (The American diet has almost no Omega 3! )

In addition, Omega 3 helps to lift your mood after about a month of use!

How Long Before Fish Oil Works on Depression to Lift Your Mood? How Long Before Fish Oil Works on Depression to Lift Your Mood?

The title says enough on this last one!

Omega-3 fatty acids increase brain volume: while reversing many aspects of neurologic aging. (full – 2010) Omega-3 fatty acids increase brain volume: while reversing many aspects of neurologic aging. - Free Online Library

And this one explains a lot more! Just a very detailed news style article- you can read it on your own!

Omega-3 PUFA Deficiency Abolishes Endocannabinoid-Linked Neuronal Functions
(news - 2011) Articles on Health Nutrition Research : Benefits of Fish, Omega-3s, Fish Oil and Polyunsaturated Fats



Get Grandma a bottle of fish, hemp seed or flax seed oil! All are high in Omega 3. Explain what you have learned! And remind her it is very good for the heart, too!

I would be partial to hemp seed oil! But not just because it comes from the cannabis plant! Fish oil can give you fishy burps- not pleasant at any age. Flax seed oil is bitter.

Hemp seed oil actually tastes pretty good (way better than flax!) and makes a good salad dressing! I add cider vinegar, Italian seasoning, garlic flakes... (and other "herbs" ). Hemp seed oil will NOT get you high and is perfectly legal. You can buy it online, or at most health food stores.

I also use hemp seed oil on my face every evening. I think I look good for my age!

Hemp Seed Oil for Skin
Hemp Seed Oil For Skin | LIVESTRONG.COM

Hemp & GLA: Good Fat Burns Bad Fat (a diet aid!)
Hemp & GLA: Good Fat Burns Bad Fat | Manitoba Harvest - Hemp Foods and Oils

Efficacy of dietary hempseed oil in patients with atopic dermatitis.
Home - PubMed - NCBI

How Hemp Seed Oil Can Help Your Arthritis
How Hemp Seed Oil Can Help Your Arthritis - Free Online Library


Hemp seed oil can provide a non-confrontational, and legal, way to introduce your female relatives to cannabis as something other than the "devil's weed with roots in hell"! What will they think of hemp seed oil- a "fountain of youth", that eases arthritis and helps you lose weight? (Do you have any idea how much American women spend on anti-aging products?)

EDUCATE! Once the facts are known about what cannabis can do, the need for legalization becomes obvious!



Granny

 

fuck granny, you lost me this time.



.

 

She can get all the Porn subscription's she wants.

 

Sorry- short version- Mice that don't have these things called CB1 receptors look older and get deaf and senile at about half the age as normal mice. You need Omega 3 to make these receptors that keep you (or mice) young-looking and clear-headed. By giving Grandma some Omega 3, she will age slower and feel better! It is good for her heart too.

Omega 3 can be found in hemp seed oil which won't get you high and tastes good enough to make salad dressings with. It also helps you lose weight and eases arthritis! Fish oil and flax seed oil are other sources of Omega 3.

Since most women fear aging, Omega 3 is an easy way to introduce hemp products in a way that isn't "scary" or illegal.

And CB1 receptors are the ones that get you high! (And 1000 other things- like kill cancer cells and fight depression)