just out of curiosity, you mentioned that butter wasn't the best.
what would be the best thing to mix the herb with in this instance?
You want an oil
that is as pure as possible, and milk-solid/protein and water free, so it reduces the risk of harboring any harmful bacteria.
Coconut oil, clarified butter, palm oil, or lastly olive oil would be good in this instance, however, when you take cannabis as a suppository
you are in effect bypassing the liver to a great extent
This can be a good, or
a bad thing, depending on your desired outcome.
If you have liver, or upper digestive tract problems, tumors, or cancers in that general region which you are trying to treat with cannabis, for instance, you will want to take your meds in such a way that allows for the most direct exposure and contact possible. That would be oral digestion and portal vein absorption.
And, just as important to some patients (and recreational users...), your liver also causes additional cannabinoid conversion
and further potentiates and intensifies
the effect of your cannabinoids, as they pass through.
When your liver is not 'starving', it will not burn through and over-metabolize your cannabinoids, but instead it will allow some though as the active D9-THC, and it converts
the rest to a more powerful,
more active (some say, by up to 5-times) form, known as 11-OH-THC
If you use a canna (or any) suppository, the medical community has found that the majority, or almost all (between %60 - %90) of liver conversion and exposure potential is lost.
What's worse, if a patient uses one of the more common, too-available oil sources, high in LCTs (Palm, Olive, Corn), rather than S/MCTs (butter, coconut oil etc.), you'll achieve almost zero liver conversion with a suppository.
But, I mentioned there was a positive to suppository use; bypassing the liver, reducing its contact with cannabinoids, can actually be very good
and even crucial, for certain patients who need to medicate to control their nausea
and peak their appetites
, before eating..... they may not be able to swallow even a capsule, let alone an entire brownie to get their dose, but a suppository will still at least deliver the cannabinoids as they are, in their current state, through the cellular walls in veins (known as 'lower-mid hemorrhoidal veins') which then enter vessels that drain into the inferior vena cava, effectively entering the blood stream this way, rather than passing through the liver before distribution.
If you simply can not eat for many hours before taking an edible, to prime your liver (when first waking up in the morning for instance), and if you can not even stomach an edible which could at least partially satisfy your liver with some of its increased fat and sugar content, then taking a usually-potent capsule orally, can cause its potency to be over-metabolized and destroyed by the liver. When this is the case, a suppository is the ideal
A patient can
achieve decent medicinal effect this way.... but if he had instead been able to 'feed' his liver a small oily meal to avoid over-metabolizing and burning up the cannabinoids upon entry, and if he'd been able to consume his dose orally
an hour or so later, he would have experienced MUCH more pronounced effects, from the same amount of material, due to the additional conversion that takes place in the liver. For the best effect, if a suppository is required
, a SCT/MCT oil is your best option if you want to direct the most potency through your liver.
So it really depends on what you're going for, or your desired outcome... if you need to medicate with a more mild sensation, with increased energy, fewer sedative effects, and less potential for pain-relief, then the suppository and sublingual/buccal administration methods for cannabis-based meds would be the way to go. Keep in mind that the dose can be increased dramatically when using suppository or sublingual (under the tongue) absorption, withoutfeeling as much increased sensation
(this is good for MS patients, and those patients who require high doses of medicine to combat tumors and cancers, but wish to maintain a certain level of functionality). This may seem counterproductive for those looking for sedative, or recreational benefits.
But if you need pain relief, rest, sedation and sleep, so you can recover and heal, along
with the regenerative and other medicinal benefits of cannabis, then oral-digestive administration would be the best route. Remember that this can provide more pronounced, and more powerful sensations, from less material. So if you're enjoying cannabis recreationally, digestion is probably the best way to go
To learn how to make this (or your trimmings...)
See the link below:
(First Page, contains detailed information on decarboxylation
, or cannabinoid conversion..
decarboxylation is the process of activating your cannabinoids 'potency' by removing the
carboxyl group in the form of carbon dioxide and water vapor, converting your cannabinoids
from their acid, to their more potent delta forms): Photo Tutorial: Highly Activated Med Grade Bioavailable Canna & Hash Oil, Edibles, Drinkables and more...
The above link also contains recipes on the first page for.... Capsules
... these may be taken orally, or as a suppository
. http://forum.grassci...nished-caps-jpg Glycerin tincture
may also be used, but must either be delivered immediately after encapsulation to avoid the capsule breaking down, or it must be simply injected using a soft, blunt-ended syringe, which for most patients can be a bit more challenging at first.
Hope this helps!