Grandfather with arthritis

My grandfather has arthritis and is in great pain. He's having trouble walking or moving to use the restroom. He's on many medications (some not for the arthritis) but hes using 200mg of Celebrex and i'm sure that its doing damage to his liver. I was wondering if I should give my grandfather an edible (less than normal) and see if that could help relieve his pain. Is this a good idea? Would this help his arthritis?

It'll help. Ask him.

make sure he knows whats going on, dont just be like "here grandpa try this cookie i made"

Well i don't think that he will ever try it because he grew up with the anti-drug propaganda.

well tell him otherwise he will freak out

Just ask about it, don't give it to him without him knowing. If he says no then there's nothing you can do.

My grandfather has arthritis and is in great pain. He's having trouble walking or moving to use the restroom. He's on many medications (some not for the arthritis) but hes using 200mg of Celebrex and i'm sure that its doing damage to his liver. I was wondering if I should give my grandfather an edible (less than normal) and see if that could help relieve his pain. Is this a good idea? Would this help his arthritis?

He needs a good topical ointment, oil or tincture made from MMJ and Celebrex is part of why I'm here only it was hurting my kidneys.

Edited by Asthmatic, 18 July 2012 - 09:27 PM.

Use a cream or lotion he can rub into his hand. My friend did this and his grandma just thought it was from the store and took her pain away. She didn't get high from using it this way.

Edited by Windex83, 19 July 2012 - 01:11 AM.

Use a cream or lotion he can rub into his hand. My friend did this and his grandma just thought it was from the store and took her pain away. You dont get high from using it this way.

Yes we can get high this way. It is a dose dependent question of how much area the patient has to cover and how strong the compounder makes the topical. The patient should be an active participant in choosing the product. Some work better than others we all have our own taste in which ones we like and don't like. I only need my topical once a day but have quite a bit of real estate to cover so I use my topical at bed time and when things go as planned sleep through the high.

Edited by Asthmatic, 18 July 2012 - 09:32 PM.

Would a very light amount of lotion (not enough to get high) be enough to stop his pain, or at least take the edge off?

As was said before, don't give your grandfather anything without his consent! Edibles are very unpredictable, and it is all to easy to have one bite too many!

Now to counter act all the DARE info, you may want to show him a few studies or articles about cannabis and arthritis. I happen to have a few..... They range from simple news articles to some heavy, incomprehensible "Sci-Speak".

ANTI-EDEMA AND ANALGESIC PROPERTIES OF Δ9-TETRAHYDROCANNABINOL (THC) (abst- 1973)
ANTI-EDEMA AND ANALGESIC PROPERTIES OF

Analgesic and antiinflammatory activity of constituents of Cannabis sativa L.
(full - 1988) http://www.ukcia.org...nstituents.html

US Patent 6132762 - Transcutaneous application of marijuana (full - 2000)
Transcutaneous application of marijuana - US Patent 6132762 Full Text

Immunoactive cannabinoids: Therapeutic prospects for marijuana constituents
(full - 2000) Immunoactive cannabinoids: Therapeutic prospects for marijuana constituents

The nonpsychoactive cannabis constituent cannabidiol is an oral anti-arthritic therapeutic in murine collagen-induced arthritis (full - 2000) From the Cover: The nonpsychoactive cannabis constituent cannabidiol is an oral anti-arthritic therapeutic in murine collagen-induced arthritis

Marijuana Extract Helps Arthritis Pain (news - 2000)
http://www.prohealth...e.cfm?libid=552

Anandamide activates peripheral nociceptors in normal and arthritic rat knee joints (full - 2001) Anandamide activates peripheral nociceptors in normal and arthritic rat knee joints

Cannabidiol-transdermal delivery and anti-inflammatory effect in a murine model.
(abst - 2003) Cannabidiol-transdermal delivery and anti-... [J Control Release. 2003] - PubMed - NCBI

Cannabis May Suppress Immune System (news - 2003)
Cannabis May Suppress Immune System

A novel synthetic, nonpsychoactive cannabinoid acid (HU-320) with antiinflammatory properties in murine collagen-induced arthritis. (full- 2004) A novel synthetic, nonpsychoactive cannabinoid acid (HU-320) with antiinflammatory properties in murine collagen-induced arthritis - Sumariwalla - 2004 - Arthritis & Rheumatism - Wiley Online Library

Ajulemic acid (IP-751): Synthesis, proof of principle, toxicity studies, and clinical trials (abst - 2005) Ajulemic acid (IP-751): Synthesis, proof of principle, toxicity studies, and clinical trials

Rheumatoid arthritis, Cannabis based medicine eases pain and suppresses disease
(news - 2005) Rheumatoid arthritis, cannabis based medicine eases pain and suppresses disease

Cannabis-Based Drug Relieves Arthritis Pain (news - 2005)
http://www.medpageto.../Arthritis/2097

First study to use a cannabis-based medicine for treating rheumatoid arthritis
(news - 2005) First study to use a cannabis-based medicine for treating rheumatoid arthritis

Pot-Based Drug Promising for Arthritis (news - 2005)
Pot-Based Drug Promising for Arthritis

Cannabis-based medicine relieves the pain of rheumatoid arthritis and suppresses the disease (news – 2005) Cannabis-based medicine relieves the pain of rheumatoid arthritis and suppresses the disease

Preliminary assessment of the efficacy, tolerability and safety of a cannabis-based medicine (Sativex) in the treatment of pain caused by rheumatoid arthritis (full - 2006)
http://rheumatology....ourcetype=HWCIT

The use of a cannabis-based medicine (Sativex) in the treatment of pain caused by rheumatoid arthritis (letter - 2006) The use of a cannabis-based medicine (Sativex) in the treatment of pain caused by rheumatoid arthritis

Arthritis and cannabinoids: HU-210 and Win-55,212-2 prevent IL-1alpha-induced matrix degradation in bovine articular chondrocytes in-vitro. (abst - 2006) Arthritis and cannabinoids: HU-210 and Win... [J Pharm Pharmacol. 2006] - PubMed - NCBI

The Cannabinergic System as a Target for Anti-inflammatory Therapies (abst - 2006)
ingentaconnect The Cannabinergic System as a Target for Anti-inflammatory Therap...

SAFETY AND TOLERABILITY OF LONG-TERM TREATMENT WITH A CANNABIS-BASED MEDICINE (SATIVEX) IN PATIENTS WITH RHEUMATOID ARTHRITIS (abst - 2006)
Restricted Maintenance Sign In Page

In vivo effects of CB2 receptor-selective cannabinoids on the vasculature of normal and arthritic rat knee joints (full - 2007) In vivo effects of CB2 receptor-selective cannabinoids on the vasculature of normal and arthritic rat knee joints

Arthritis and pain. Future targets to control osteoarthritis pain. (full - 2007) Arthritis and pain. Future targets to control osteoarthritis pain

INHIBITORY EFFECT OF CANNABINOID AGONISTS ON CYTOKINE PRODUCTION IN HUMAN OSTEOARTRITHIC AND RHEUMATOID FIBROBLAST-LIKE SYNOVIOCYTES (abst - 2007)
Restricted Maintenance Sign In Page

Suppression of fibroblast metalloproteinases by ajulemic acid, a nonpsychoactive cannabinoid acid. (abst - 2007) Suppression of fibroblast metalloproteinases ... [J Cell Biochem. 2007] - PubMed - NCBI

The antinociceptive effect of Delta9-tetrahydrocannabinol in the arthritic rat involves the CB(2) cannabinoid receptor. (abst - 2007)
Unbound MEDLINE | The antinociceptive effect of Delta9-tetrahydrocannabinol in the arthritic rat involves the CB(2) cannabinoid receptor. PubMed Journal article abstract

Synergy between Delta(9)-tetrahydrocannabinol and morphine in the arthritic rat
(abst - 2007)
Unbound MEDLINE | Synergy between delta9-tetrahydrocannabinol and morphine in the arthritic rat. PubMed Journal article abstract

Characterisation of the cannabinoid receptor system in synovial tissue and fluid in patients with osteoarthritis and rheumatoid arthritis. (full - 2008) Characterisation of the cannabinoid receptor system in synovial tissue and fluid in patients with osteoarthritis and rheumatoid arthritis

In vivo effects of CB2 receptor-selective cannabinoids on the vasculature of normal and arthritic rat knee joints (full - 2008) In vivo effects of CB2 receptor-selective cannabinoids on the vasculature of normal and arthritic rat knee joints

Cannabinoid-mediated antinociception is enhanced in rat osteoarthritic knees.
(full – 2008) Cannabinoid-mediated antinociception is enhanced in rat osteoarthritic knees - Schuelert - 2007 - Arthritis & Rheumatism - Wiley Online Library

CB2 cannabinoid receptor agonist JWH-015 modulates human monocyte migration through defined intracellular signaling pathways. (full – 2008) CB2 cannabinoid receptor agonist JWH-015 modulates human monocyte migration through defined intracellular signaling pathways

How Cannabis Compares to other treatments (full - 2008)
Medical Marijuana - GI brochure

Suppression of human macrophage interleukin-6 by a nonpsychoactive cannabinoid acid. (abst - 2008) Home - PubMed - NCBI

Ajulemic acid, a nonpsychoactive cannabinoid acid, suppresses osteoclastogenesis in mononuclear precursor cells and induces apoptosis in mature osteoclast-like cells.
(abst - 2008) Ajulemic acid, a nonpsychoactive cannabinoid ... [J Cell Physiol. 2008] - PubMed - NCBI

Anti-inflammatory compound from cannabis found in herbs (news - 2008)
Anti-inflammatory compound from cannabis found in herbs

Ajulemic acid, a synthetic cannabinoid, increases formation of the endogenous proresolving and anti-inflammatory eicosanoid, lipoxin A4 (full - 2009)
Ajulemic acid, a synthetic cannabinoid, increases formation of the endogenous proresolving and anti-inflammatory eicosanoid, lipoxin A4

Cannabinoids as novel anti-inflammatory drugs. (full - 2009)
Cannabinoids as novel anti-inflammatory drugs

How Hemp Seed Oil Can Help Your Arthritis (news – 2009)
How Hemp Seed Oil Can Help Your Arthritis - Free Online Library

Tissue Engineering of Cartilage; Can Cannabinoids Help? (full – 2010)
http://www.mdpi.com/...47/3/9/2970/pdf

Cannabinoid-induced apoptosis in immune cells as a pathway to immunosuppression. (full - 2010) Cannabinoid-induced apoptosis in immune cells as a pathway to immunosuppression

Tonic modulation of spinal hyperexcitability by the endocannabinoid receptor system in a rat model of osteoarthritis pain. (full – 2010) Tonic Modulation of Spinal Hyperexcitability by the Endocannabinoid Receptor System in a Rat Model of Osteoarthritis Pain

Local application of the endocannabinoid hydrolysis inhibitor URB597 reduces nociception in spontaneous and chemically induced models of osteoarthritis.
(abst – 2010)
Unbound MEDLINE | Local application of the endocannabinoid hydrolysis inhibitor URB597 reduces nociception in spontaneous and chemically induced models of osteoarthritis. PubMed Journal article abstract

Paradoxical effects of the cannabinoid CB2 receptor agonist GW405833 on rat osteoarthritic knee joint pain. (abst – 2010) Paradoxical effects of the cannabin... [Osteoarthritis Cartilage. 2010] - PubMed - NCBI

Cannabinoids for Treatment of Chronic Non-Cancer Pain; a Systematic Review of Randomized Trials. (abst – 2011) Cannabinoids for treatment of chronic no... [Br J Clin Pharmacol. 2011] - PubMed - NCBI

Cannabidiol as an emergent therapeutic strategy for lessening the impact of inflammation on oxidative stress. (abst – 2011) Cannabidiol as an emergent therapeutic s... [Free Radic Biol Med. 2011] - PubMed - NCBI

The abnormal cannabidiol analogue O-1602 reduces nociception in a rat model of acute arthritis via the putative cannabinoid receptor GPR55. (abst – 2011) The abnormal cannabidiol analogue O-1602 reduc... [Neurosci Lett. 2011] - PubMed - NCBI

Fatty acid amide hydrolase blockade attenuates the development of collagen-induced arthritis and related thermal hyperalgesia in mice. (abst - 2011)
Fatty acid amide hydrolase blockade ... [Pharmacol Biochem Behav. 2011] - PubMed - NCBI

Platelet-rich plasma loaded hydrogel scaffold enhances chondrogenic differentiation and maturation with up-regulation of CB1 and CB2. (abst – 2012)
Platelet-rich plasma loaded hydrogel scaff... [J Control Release. 2012] - PubMed - NCBI

Effects of Peptide and Lipid Endocannabinoids on Arthritic Pain at Spinal Level.
(abst – 2012) The effects of peptide and lipid endocannabinoi... [Anesth Analg. 2012] - PubMed - NCBI

Lack of effect of chronic pre-treatment with the FAAH inhibitor URB597 on inflammatory pain behaviour: evidence for plastic changes in the endocannabinoid system. (abst – 2012) Lack of effect of chronic pre-treatment with ... [Br J Pharmacol. 2012] - PubMed - NCBI

Cannabinoids: novel therapies for arthritis? (abst – 2012) Cannabinoids: novel therapies for arthritis? [Future Med Chem. 2012] - PubMed - NCBI

Hope that helps.


Granny

Yes we can get high this way. It is a dose dependent question of how much area the patient has to cover and how strong the compounder makes the topical. The patient should be an active participant in choosing the product. Some work better than others we all have our own taste in which ones we like and don't like. I only need my topical once a day but have quite a bit of real estate to cover so I use my topical at bed time and when things go as planned sleep through the high.

Ive never heard of anyone else getting high off of hand creme. It does not go to the brain and stays local. Topical applications have no psychoactive effect. Google it.

Make a root balm or a balm using the whole plant (buds, stems, leaves, roots). I have muscle spasms and a bad back. I rub this stuff on it before I go to bed and when I wake up. It's the only thing that relieves the pain without getting me intoxicated. The most I've experienced was a slight buzz when I slathered it on thick, and that was using the whole plant.

CannaRoot Balm

One or Two Root Balls, depending on size
Coconut oil, 2-4 cups, the more the better
Water, 1-2 cups (half of the coconut oil)
Beeswax (optional, can help keep the finished material hardened until use, more of a texture thing)

Put all ingredients (except beeswax) into your crockpot

Cook on low or high heat, until it is really simmering (200 degrees), 12-14 hours

Turn off heat and let rest for 6-10 hrs

Repeat on and off for 2-3 days, adding water as needed, this helps get the medicine goodness out into the coconut oil.

Strain the roots and miscellaneous dirt out of coconut / water mixture using women's stockings.

place in refrigerator in a bowl overnight, the coconut oil and water will seperate.

poke the hardened oil in a couple places and pour out the water

Depending on how the mixture looks, you might warm up, strain through cheese cloth (or stockings), and place in refrigerator one more night.

pour off the water again.

Warm up gently, add some beeswax if you've got it ( 3:1 oil:wax), until melted, mix thoroughly, stand mixers work great. pour into airtight containers. Baby jars work great. Store in fridge for longer storage. keep a jar in the bathroom to put on after a hot shower while your pores are open. keep a jar by the bed to rub on achy joints before bed.

Optional ending: Adding some Vitamin E will help increase the shelf-life of the balm and you can add some aromatic extracts if you'd like too. I like to add lavender extract.

Edited by Brownbearbauer, 19 July 2012 - 01:51 PM.

FYI- Beeswax can be found at craft stores, sewing shops, and sometimes, health food stores.

that is his choice not yours.
Dont just drug him, ask him if he wants some herb for the pain..
Ps. Celebrex sux, just hyped up tylenol pretty much

Ive never heard of anyone else getting high off of hand creme. It does not go to the brain and stays local. Topical applications have no psychoactive effect. Google it.

I take it daily and it does, I don't care what Google says. It does not have to but it can if you use enough and it is bioavailable enough. Small doses won't normally, but I've seen exceptions. It is about formula and real-estate. I cover every joint in my body except my left knee. It made me high all by it's self before I started treating my Asthma with MMJ too. I don't smoke it and rarely vape.

Edited by Asthmatic, 22 July 2012 - 10:45 PM.

Try getting Grandpa to show these to his rheumatologist or who ever is treating his arthritis and ask for a plain English translation from the Dr.

Tissue Engineering of Cartilage; Can Cannabinoids Help?
http://www.mdpi.com/...47/3/9/2970/pdf

If he likes what he hears when the good Dr. translates it he should then ask if a topical ointment could deliver enough medicine to his joints to improve his prognosis.

Cannabinoid Receptor Type 1 Protects against Age-Related Ostioprosis
Redirection page

I just like the 2nd one having medication related bone loss my self.

Edited by Asthmatic, 24 July 2012 - 02:26 AM.

Hello!
My elderly mother asked me to investigate what options she might have available to her as a rheumatoid arthritis patient living in Texas. She had heard that it is possible to make a non-psychoactive cream using marijuana that would relieve her symptoms, but since she lives in a rather conservative state, she is understandably concerned about legality.
Is there a version of this remedy available that would not land her in jail? Where could she obtain it?

(edit) It actually looks like using hemp to make cream may be a viable option -- has anyone actually done this? The idea is to get a good source of cannabidiol without the THC -- would this work? Where would one go to obtain hemp for something like this?

Thank you for your help!

Edited by LaughtLikeWater, 11 December 2012 - 03:30 AM.
additional information

Hello!
My elderly mother asked me to investigate what options she might have available to her as a rheumatoid arthritis patient living in Texas. She had heard that it is possible to make a non-psychoactive cream using marijuana that would relieve her symptoms, but since she lives in a rather conservative state, she is understandably concerned about legality.
Is there a version of this remedy available that would not land her in jail? Where could she obtain it?

(edit) It actually looks like using hemp to make cream may be a viable option -- has anyone actually done this? The idea is to get a good source of cannabidiol without the THC -- would this work? Where would one go to obtain hemp for something like this?

Thank you for your help!

If she wants to stay legal in a non-green state Fish Oil high in EPA and or DHA is the endocannabinoid version of MMJ.

Search "EPA DHA Cannabinoid"
Then search "EPA DHA rheumatoid arthritis"

Thank you so much for your help! I will check it out.