The only effect I've noticed is a rapidly increasing tolerance (nothing to boast about - it's just getting bloody expensive!)...
Obviously there's all the other disadvantages to toking lots... social segregation is a biggie, then there's the health factor.
And everyone acts a little dopey some of the time... This could be because you've smoked a stupidly large (and I mean larger than the average smoker's intake) amount of skunk and it's become imbedded in your system, but it's most likely you're just tired from having been up all night toking weed, or maybe even stoned
But I've hardly been toking all my life (still plenty to go fingers-crossed) so I'm not the best placed caner to give advice.
Henrx