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Old 07-05-2008, 08:45 AM
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Shrooms and Anti-depressants

I was wondering if it's true that shrooms don't "work" when you're on anti-depressants.. I mean, I would say it's true, because I tried them twice while I was on them, and once when I was off of them for a week beforehand, and I only tripped the third time. But I also don't know if I took enough to even trip the first two times. Anyone know anything about this?
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Old 07-05-2008, 08:47 AM
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Dont dont dont dont dont.

Taking psyilocybin containing mushrooms while on an MAOI can dramatically increase the effects of the experience. MAOIs are most commonly found in the prescription anti-depressants Nardil (phenelzine), Parnate (tranylcypromine), Marplan (isocarboxazid), Eldepryl (l-deprenyl), and Aurorex or Manerix (moclobemide). Ayahuasca also contains MAOIs (harmine and harmaline). Check with your doctor if you are not sure whether your prescription medication is an MAOI.
 
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Old 07-05-2008, 08:51 AM
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Well I'm not on them anymore, and I'm not going to trip anytime soon. I was just wondering. But it certainly didn't increase anything, lol.
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Old 07-05-2008, 08:53 AM
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You're lucky. It's a psychological recipe for disaster in most cases.
 
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Old 07-05-2008, 08:59 AM
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Are SSRIs different from MAOIs? Cos the one I was on was an SSRI.
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Old 07-05-2008, 09:01 AM
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Yes they are. Selective serotonin reuptake inhibitors.
 
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Old 07-05-2008, 09:04 AM
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Well, I meant different in the way they react with shrooms. I know they're different types of medication.
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Old 07-05-2008, 09:13 AM
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Sorry, my friends tell me im way too literal

They ask what a cloud looks like and I say "a bunch of suspended water and ice particles".
 
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Old 07-05-2008, 05:53 PM
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MAOI's increase shroom effects, and it is debated what effects SSRIs have on a trip. I take an SSRI and I tripped pretty hard off of 2.1.
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Old 07-06-2008, 07:00 AM
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I've noticed that the first time you take a psychadelic you trip pretty hard as long as its a reasonable dose. (1/2 8th of shrooms) some may scoff at that small amount but there are many who have had quite profound trips from it. but i do know that when i took zoloft and later prozac, both SSRI's, my tolerance for psychadelics and ecstasy went through the roof. Even now i have to take more LSD, shrooms, or E to have a comparable experience to my friends. I dont take those drugs much at all so i know its not a natural tolerance. And im of average build , 5' 11" 160 lbs, so dont think it could be my size.
 
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