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Hiya, i think if you could split the room in two for veg and flowering or make two cabs for the grow, this will help keep the yeild up by havesting every 30 ish days. Because hot air rises and cold air falls it is worth puttin the extract fans at the highest point you can an the intake as low as you can. As for how many plants it depends on lights used, if you could afford several 600w HPS and MH lights you could have 8 plants constantly vegging and 8 flowering easily with good yeilding strain could see alot of bud.
I recommend searching these forums for more info on setups ect.
Glad i could help.
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