View Single Post
  #11 (permalink)  
Old 07-05-2009, 07:57 AM
Storm Crow is offline  
Storm Crow has been around the CityStorm Crow has been around the CityStorm Crow has been around the CityStorm Crow has been around the CityStorm Crow has been around the CityStorm Crow has been around the CityStorm Crow has been around the CityStorm Crow has been around the CityStorm Crow has been around the CityStorm Crow has been around the CityStorm Crow has been around the City
Storm Crow
Registered User
Join Date: Jul 2008
Posts: 924
Re: Why is weed some kind of wonderdrug?

Let's start with a couple of 2009 THC studies-

Inhibition of Glioma Growth in Vivo by Selective Activation of the CB2
Cannabinoid Receptor1
http://cancerres.aacrjournals.org/cg...61/15/5784.pdf

They did the usual mouse injected with human cancer cells study and showed that the tumors regressed (gross photos included) and then....

"Finally, we analyzed the tumors of 2 patients enrolled in a clinical trial aimed at investigating the effect of THC on recurrent glioblastoma multiforme. The patients were subjected to intracranial THC administration, and biopsies were taken before and after the treatment. "

Their conclusions-
"These findings describe a mechanism by which THC can promote the autophagic death of human and mouse cancer cells and provide evidence that cannabinoid administration may be an effective therapeutic strategy for targeting human cancers."

"THC-induced autophagy promotes the apoptotic death of cancer cells."


Now a second study done on the same tumor patients also revealed that THC slowed the growth of the blood vessels that fed the gliomas.


Cannabinoids Inhibit the Vascular Endothelial Growth Factor Pathway in Gliomas -- Blázquez et al. 64 (16): 5617 -- Cancer Research

Their findings-
"Here, we report that cannabinoid administration inhibits the VEGF pathway in cultured glioma cells, in glioma-bearing mice, and in two patients with glioblastoma multiforme."

So THC slowed the chemical process that promotes the growth of blood vessels to cancers in petri dishes, in mice, AND in humans.

So just how are these results like these "a bandaid over symptoms" or the "sideeffects of being high"? The tumors shrank, the blood vessels growth slowed.




Vocabulary for the "science challenged"

autophagic/ autophagy= literally self-eating

apoptopic/apoptosis = cell death

intracranial= directly into the brain

vascular endothelial growth factor (VEGF)= stuff that makes the blood vessels grow faster.

glioma = brain cancer

glioblastoma multiforme = nasty type of brain cancer that often comes back

And lastly just for you, Dale-

micromolar -
A concentration of 1/1,000,000 (one millionth) molecular weight per liter (mol/L). Not a heck of a lot, in other words.


Granny
__________________
"If the truth won't do, then something is wrong!"
Granny's Granddad- Rev. John Schwabenland

Need MMJ Studies? Try Granny's "Master list"-
New format- http://cannalink.org/granny/ (YOU can add studies!)
Simple format- http://forum.grasscity.com/medical-marijuana/436257-granny-storm-crows-list-july-2009-a.html

Want your own free copy of my list? Email us at-
i.wantgrannyslist(at)greenpassion.org


Last edited by Storm Crow; 07-05-2009 at 08:00 AM.
  Reply With Quote