[HighVibes]

so i just did a bunch of research and i found out that taking DXM while taking SSRI's (antidepressants, such as Zoloft, which i currently take every day) on a regular basis is harmful, and sometimes fatal. heres the section of a DXM website i found about it:

6.2.9 Serotonin Syndrome


Category: Theoretical (especially DXM + antidepressants)
Serotonin syndrome is a recently-identified condition that typically occurs when combining serotonergic drugs (i.e., drugs that stimulate, or mimic, serotonin activity in the brain). Most of these drugs are antidepressants (MAOIs, SSRIs such as ProzacTM or ZoloftTM, tricyclics, lithium, and atypical antidepressants); others include buspirone (BuSparTM), MDMA (ecstasy) and other phenethylamines, tryptophan, harmine and harmaline (both recreational MAOIs), and possibly serotonergic hallucinogens such as LSD, psilocybin, and DMT. Phentermine, fenfulramine, and phen-fen can also cause serotonin syndrome when combined with DXM.
DXM induces a release of serotonin, and while it has never been demonstrated to cause serotonin syndrome by itself, it has been shown to do so in combination with other serotonergics (365). In particular, combining SSRIs and DXM may be risky; one paper found serotonin syndrome from an SSRI combined with DXM with a concurrent vascular disease (364).
Serotonin syndrome is indicated by a combination of three sets of symptoms: changes in mental status, autonomic dysfunction, and neuromuscular abnormalities. Specific symptoms include:

• Changes in Mental Status
  • hypomania
  • confusion
  • agitation
• Autonomic Dysfunction
  • diarrhea
  • low-grade fever
  • diaphoresis (sweating)
  • shivering
• Neuromuscular Abnormalities
  • myoclonus (sudden, brief muscle spasms)
  • hyperreflexia (exagerrated reflexes)
  • ataxia (incoordination and clumsiness)

Yes, there is some overlap (e.g., shivering can considered as an autonomic dysfunction or a neuromuscular abnormality).
More serious symptoms can include rhabdomyolysis (basically, your muscle cells break open and leak muscle-cell-parts into your bloodstream, poisoning you), coma, and death. Serotonin syndrome deaths are rare, however.
Treatment of serotonin syndrome requires medical intervention, and consists of supporting measures to treat the symptoms, and possibly antiserotonergic drugs. Benzodiazepines (such as ValiumTM) have also been used with considerable success (366).
The astute among you will notice that many of these "symptoms" are characteristics of DXM intoxication. In fact, many serotonergic drugs can cause these symptoms. The question is whether or not the symptoms become severe and numerous. At least one symptom from each of the three categories is generally required for a diagnosis of serotonin syndrome.
Once again, if in doubt, see a doctor. And avoid using DXM in combination with any antidepressant. Remember, combining DXM with a MAOI has been repeatedly fatal!




I'm so pissed. I'm 18 and a senior in high school and ive robotripped only once before (but it was the wrong kind of medicine that had several active ingredients, so i got kinda sick), and by coindence all my friends are working tonight. and i cant smoke cuz im taking a break for a while. so i'm stuck at home, and i have a bottle of "wal-tussin" gel caps i was planning on robotripping off of, until i saw this article. im so disappointed! any thoughts?